| Train | Source | Destination | Days Run from Rameswaram |
| 06080 - Cape Ms Sf Special | Rameswaram (RMM) | Tirupati (TPTY) | Tue |
| # | Station | Arrival | Departure | Halt | Distance | Day |
| 1 | Rameswaram (RMM) | Source | 04:30 PM | 0 Mins | 0 KMs | 1 |
| 2 | Mandapam (MMM) | 04:53 PM | 04:55 PM | 2 Mins | 17 KMs | 1 |
| 3 | Ramanathapuram (RMD) | 05:18 PM | 05:20 PM | 2 Mins | 54 KMs | 1 |
| 4 | Paramakkudi (PMK) | 05:43 PM | 05:45 PM | 2 Mins | 90 KMs | 1 |
| 5 | Manamadurai Jn (MNM) | 06:15 PM | 06:20 PM | 5 Mins | 114 KMs | 1 |
| 6 | Madurai Jn (MDU) | 07:20 PM | 07:25 PM | 5 Mins | 161 KMs | 1 |
| 7 | Kodaikanal Road (KQN) | 07:58 PM | 08:00 PM | 2 Mins | 201 KMs | 1 |
| 8 | Dindigul Jn (DG) | 08:45 PM | 08:50 PM | 5 Mins | 227 KMs | 1 |
| 9 | Tiruchchirappalli Jn. (TPJ) | 10:10 PM | 10:15 PM | 5 Mins | 321 KMs | 1 |
| 10 | Thanjavur Jn. (TJ) | 11:05 PM | 11:07 PM | 2 Mins | 371 KMs | 1 |
| 11 | Papanasam (PML) | 11:27 PM | 11:28 PM | 1 Mins | 396 KMs | 1 |
| 12 | Kumbakonam (KMU) | 11:38 PM | 11:40 PM | 2 Mins | 410 KMs | 1 |
| 13 | Mayiladuturai Jn (MV) | 12:13 AM | 12:15 AM | 2 Mins | 442 KMs | 2 |
| 14 | Sirkazhi (SY) | 12:37 AM | 12:38 AM | 1 Mins | 462 KMs | 2 |
| 15 | Chidambaram (CDM) | 12:56 AM | 12:58 AM | 2 Mins | 478 KMs | 2 |
| 16 | Tiruppadiripuliyur (TDPR) | 01:49 AM | 01:50 AM | 1 Mins | 521 KMs | 2 |
| 17 | Villupuram Jn (VM) | 03:05 AM | 03:10 AM | 5 Mins | 563 KMs | 2 |
| 18 | Tiruvannamalai (TNM) | 04:43 AM | 04:45 AM | 2 Mins | 631 KMs | 2 |
| 19 | Arni Road (ARV) | 05:19 AM | 05:20 AM | 1 Mins | 678 KMs | 2 |
| 20 | Vellore Cantonment (VLR) | 06:28 AM | 06:30 AM | 2 Mins | 714 KMs | 2 |
| 21 | Katpadi Jn (KPD) | 07:40 AM | 07:45 AM | 5 Mins | 724 KMs | 2 |
| 22 | Pakala Jn (PAK) | 08:58 AM | 09:00 AM | 2 Mins | 786 KMs | 2 |
| 23 | Tirupati (TPTY) | 10:10 AM | Destination | 0 Mins | 828 KMs | 2 |